Fes1 is a conserved armadillo repeat-containing Hsp70 nucleotide exchange factor important for growth at high temperature, proteasomal protein degradation and prion propagation.Depleting or mutating Fes1 induces a stress response and causes defects in these processes that are ascribed solely to K-7 disruption of Fes1 regulation of Hsp70.Here, we fi
The NR2F2 gene encodes the transcription factor COUP-TFII, which is upregulated in embryonic mesoderm.Heterozygous variants in NR2F2 cause a spectrum of congenital anomalies including cardiac and gonadal phenotypes.We generated heterozygous (MCRIi030-A-1) and homozygous (MCRIi030-A-2) Pterostilbene NR2F2-knockout induced pluripotent stem cell (iPSC
Enterprise architecture is a method or explanation of how to plan, compile, structure, and realize company structures, business processes, information systems, and related infrastructure as well as an explanation of how to design systems that can support business needs and related technology to make vision and mission achieve results.targeted.The f
The objective involved in this article is centered on the analytical effort to contextualize the socio-spatial formation and the economy of the Pan-Amazon, as well as the regional integration processes, which we can say is closely related and associated with the development and implementation of megaprojects in the region.The Pan-Amazonian gigantis
OBJECTIVES: To identify the most cited articles in general Visors surgery published by Brazilian authors.INTRODUCTION: There are several ways for the international community to recognize the quality of a scientific article.Although controversial, the most widely used and reliable methodology to identify the importance of an article is citation anal